N Antibody, Biotin conjugated | CSB-PA318401LD01LNP

N Antibody, Biotin conjugated | CSB-PA318401LD01LNP | Cusabio

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Product Type: Polyclonal Antibody

Target Names: N

Aliases: Nucleoprotein (Nucleocapsid protein) (Protein N), N

Background: Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) . Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation (By similarity) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: P13699

Host Species: Rabbit

Species Reactivity: Lassa virus

Immunogen: Recombinant Lassa virus Nucleoprotein protein (1-569AA)

Immunogen Species: Lassa virus

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others