MME Antibody | CSB-PA014653LA01HU

MME Antibody | CSB-PA014653LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MME

Aliases: Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10), MME, EPN

Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535) . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991) . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675) . Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P08473

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Neprilysin protein (386-617AA)

Immunogen Species: Homo sapiens (Human)

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:100-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: IHC:1:100-1:500

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal Transduction