MDFIC Antibody, Biotin conjugated | CSB-PA889174OD01HU

MDFIC Antibody, Biotin conjugated | CSB-PA889174OD01HU | Cusabio

MDFIC Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MDFIC

Aliases: MyoD family inhibitor domain-containing protein (I-mfa domain-containing protein) (hIC), MDFIC

Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9P1T7

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cell biology;Microbiology;Stem cells