MDC1 Antibody | CSB-PA098783

MDC1 Antibody | CSB-PA098783 | Cusabio

MDC1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MDC1

Aliases: Mediator of DNA-damage checkpoint 1

Background: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q14676

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthetic peptide of human MDC1

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:100-1:300

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling