MCF2L Antibody | CSB-PA521145ESR2HU

MCF2L Antibody | CSB-PA521145ESR2HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MCF2L

Aliases: Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein), MCF2L, KIAA0362 OST

Background: Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity) . Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity) . Isoform 5 activates CDC42 (PubMed:15157669) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O15068

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Guanine nucleotide exchange factor DBS protein (850-980AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

Dilution Ratio4:

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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction