Cusabio Polyclonal Antibodies
MBNL1 Antibody, FITC conjugated | CSB-PA889088LC01HU
- SKU:
- CSB-PA889088LC01HU
- Availability:
- 3 to 7 Working Days
Description
MBNL1 Antibody, FITC conjugated | CSB-PA889088LC01HU | Cusabio
MBNL1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: MBNL1
Aliases: Muscleblind-like protein 1 (Triplet-expansion RNA-binding protein), MBNL1, EXP KIAA0428 MBNL
Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU (U/G) Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
Isotype: IgG
Conjugate: FITC
Clonality: Polyclonal
Uniport ID: Q9NR56
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Muscleblind-like protein 1 protein (1-382AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling