Cusabio Polyclonal Antibodies
MAX Antibody | CSB-PA013527KA01HU
- SKU:
- CSB-PA013527KA01HU
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul (100ug)
Description
MAX Antibody | CSB-PA013527KA01HU | Cusabio
MAX Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: MAX
Aliases: MAX; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; orf1
Background: Members of the Myc/Max/Mad network function as transcriptional regulators with roles in various aspects of cell behavior including proliferation, differentiation and apoptosis. These proteins share a common basic-helix-loop-helix leucine zipper (bHLH-ZIP) motif required for dimerization and DNA-binding. Max was originally discovered based on its ability to associate with c-Myc and found to be required for the ability of Myc to bind DNA and activate transcription. Subsequently, Max has been viewed as a central component of the transcriptional network, forming homodimers as well as heterodimers with other members of the Myc and Mad families. The association between Max and either Myc or Mad can have opposing effects on transcriptional regulation and cell behavior. The Mad family consists of four related proteins; Mad1, Mad2 (Mxi1), Mad3 and Mad4, and the more distantly related members of the bHLH-ZIP family, Mnt and Mga. Like Myc, the Mad proteins are tightly regulated with short half-lives. In general, Mad family members interfere with Myc-mediated processes such as proliferation, transformation and prevention of apoptosis by inhibiting transcription.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P61244
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human MAX
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200
Purification Method: Affinity purification
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:2000
Dilution Ratio3: IHC:1:50-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling;Cancer