Cusabio Polyclonal Antibodies
MAPT (Ab-396) Antibody | CSB-PA904096
- SKU:
- CSB-PA904096
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
MAPT (Ab-396) Antibody | CSB-PA904096 | Cusabio
MAPT (Ab-396) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: MAPT
Aliases: MAPT; Microtubule-associated protein tau; MTBT1; Neurofibrillary tangle protein; Paired helical filament-tau
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Puig B, et al. (2005) Acta Neuropathol (Berl) . 110 (3) :261-268.
DeGiorgis JA, et al. (2005) J Proteome Res. 4 (2) : 306-315.
Alonso Adel C, et al. (2004) J Biol Chem. 279 (33) : 34873-34881.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P10636
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthesized non-phosphopeptide derived from human Tau around the phosphorylation site of Serine 396.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:3000
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:3000
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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Neuroscience;Signal transduction