Cusabio Polyclonal Antibodies
MAPT (Ab-205) Antibody | CSB-PA247791
- SKU:
- CSB-PA247791
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
MAPT (Ab-205) Antibody | CSB-PA247791 | Cusabio
MAPT (Ab-205) Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: MAPT
Aliases: Neurofibrillary tangle protein; Paired helical filament-tau; MAPT; MTAPT; MTBT1
Background:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
del C Alonso A, et al. (2004) J Biol Chem; 279 (33) : 34873-81
Li G, Yin H, Kuret J (2004) J Biol Chem; 279 (16) : 15938-45
Giasson BI, et al. (2002) Biochemistry; 41 (51) : 15376-87
Liu F, et al. (2002) FEBS Lett; 530 (1-3) : 209
Taniguchi T, et al. (2001) J Biol Chem; 276 (13) : 10025-31
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P10636
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around aa.203~207 (P-G-T-P-G) derived from Human Tau.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:1000
Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Neuroscience;Signal transduction