MAP3K5 (Ab-966) Antibody | CSB-PA085364

MAP3K5 (Ab-966) Antibody | CSB-PA085364 | Cusabio

MAP3K5 (Ab-966) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MAP3K5

Aliases: ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5

Background:

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

Zhang W, et al. (2005) J Biol Chem. 280 (19) : 19036-19044.
Fujii K, et al. (2004) Oncogene. 23 (29) :5099-5104.
Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12; 279 (11) : 10442-10449.
Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96 (15) : 8511-8515.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99683

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Peptide sequence around aa.964~968 (S-I-S-L-P) derived from Human ASK1.

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:200

Dilution Ratio4: IF:1:100-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cardiovascular;Cell biology