Cusabio Polyclonal Antibodies
MAML1 Antibody | CSB-PA838784LA01HU
- SKU:
- CSB-PA838784LA01HU
- Availability:
- 3 to 7 Working Days
Description
MAML1 Antibody | CSB-PA838784LA01HU | Cusabio
MAML1 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: MAML1
Aliases: Mastermind-like protein 1 (Mam-1), MAML1, KIAA0200
Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q92585
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Mastermind-like protein 1 protein (1-45AA)
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:20-1:200
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Stem Cells
Research Areas: Stem cells