Cusabio Polyclonal Antibodies
MACROD1 Antibody, FITC conjugated | CSB-PA860244LC01HU
- SKU:
- CSB-PA860244LC01HU
- Availability:
- 3 to 7 Working Days
Description
MACROD1 Antibody, FITC conjugated | CSB-PA860244LC01HU | Cusabio
MACROD1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: MACROD1
Aliases: O-acetyl-ADP-ribose deacetylase MACROD1 (EC 3.2.2.-) (EC 3.5.1.-) (MACRO domain-containing protein 1) (Protein LRP16) ([Protein ADP-ribosylglutamate] hydrolase), MACROD1, LRP16
Background: Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity.
Isotype: IgG
Conjugate: FITC
Clonality: Polyclonal
Uniport ID: Q9BQ69
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human O-acetyl-ADP-ribose deacetylase MACROD1 protein (83-325AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Epigenetics & Nuclear Signaling;Cancer;Signal transduction