Cusabio Polyclonal Antibodies
KSR1 Antibody | CSB-PA202913
- SKU:
- CSB-PA202913
- Availability:
- 3 to 7 Working Days
Description
KSR1 Antibody | CSB-PA202913 | Cusabio
KSR1 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: KSR1
Aliases: kinase suppressor of ras 1
Background: Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGF -activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGF stimulation.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q8IVT5
Host Species: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide of human KSR1
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:5000
Dilution Ratio2: IHC:1:50-1:200
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction