KDM6A Antibody, Biotin conjugated | CSB-PA025774LD01HU

KDM6A Antibody, Biotin conjugated | CSB-PA025774LD01HU | Cusabio

KDM6A Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: KDM6A

Aliases: Lysine-specific demethylase 6A (EC 1.14.11.-) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein), KDM6A, UTX

Background: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849) . Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849) . Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529) . Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O15550

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Lysine-specific demethylase 6A protein (620-749AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling