Cusabio Polyclonal Antibodies
ITGA5 Antibody, Biotin conjugated | CSB-PA011868LD01HU
- SKU:
- CSB-PA011868LD01HU
- Availability:
- 3 to 7 Working Days
Description
ITGA5 Antibody, Biotin conjugated | CSB-PA011868LD01HU | Cusabio
ITGA5 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: ITGA5
Aliases: Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain], ITGA5, FNRA
Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877) . ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881) .
Isotype: IgG
Conjugate: Biotin
Clonality: Polyclonal
Uniport ID: P08648
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Integrin alpha-5 protein (220-472AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction;Stem cells