IST1 Antibody, Biotin conjugated | CSB-PA012171LD01HU

IST1 Antibody, Biotin conjugated | CSB-PA012171LD01HU | Cusabio

IST1 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: IST1

Aliases: IST1 homolog (hIST1) (Putative MAPK-activating protein PM28), IST1, KIAA0174

Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480) . During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712) . Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: P53990

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human IST1 homolog protein (172-284AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology