INPP5F Antibody, FITC conjugated | CSB-PA896692NC01HU

INPP5F Antibody, FITC conjugated | CSB-PA896692NC01HU | Cusabio

INPP5F Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: INPP5F

Aliases: Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.25) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 4-phosphatase 2) (hSAC2), INPP5F, KIAA0966 SAC2

Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4, 5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669) . Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669) . Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895) . Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455) . Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity) . May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity) .

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q9Y2H2

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Metabolism;Signal transduction