IFIT1 Antibody, HRP conjugated | CSB-PA011018LB01HU

IFIT1 Antibody, HRP conjugated | CSB-PA011018LB01HU | Cusabio

IFIT1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: IFIT1

Aliases: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56), IFIT1, G10P1 IFI56 IFNAI1 ISG56

Background: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism) . Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: P09914

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Interferon-induced protein with tetratricopeptide repeats 1 protein (1-181AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology