Cusabio Polyclonal Antibodies
HSPD1 Antibody, Biotin conjugated | CSB-PA010847LD01HU
- SKU:
- CSB-PA010847LD01HU
- Availability:
- 3 to 7 Working Days
Description
HSPD1 Antibody, Biotin conjugated | CSB-PA010847LD01HU | Cusabio
HSPD1 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: HSPD1
Aliases: 60 kDa heat shock protein, mitochondrial (EC 3.6.4.9) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein), HSPD1, HSP60
Background: Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376) . The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable) .
Isotype: IgG
Conjugate: Biotin
Clonality: Polyclonal
Uniport ID: P10809
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human 60 kDa heat shock protein, mitochondrial protein (225-573AA)
Immunogen Species: Homo sapiens (Human)
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Tags & Cell Markers
Research Areas: Isotype Loading Controls;Tags & Cell Markers;Signal transduction