HSD3B7 Antibody | CSB-PA861999LA01HU

HSD3B7 Antibody | CSB-PA861999LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: HSD3B7

Aliases: 3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3-beta-HSD VII) (3-beta-hydroxy-Delta (5) -C27 steroid oxidoreductase) (C (27) 3-beta-HSD) (EC 1.1.1.-) (Cholest-5-ene-3-beta, 7-alpha-diol 3-beta-dehydrogenase) (EC 1.1.1.181), HSD3B7

Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C (19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870) . Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha, 25-dihydroxycholesterol (7-alpha, 25-OHC) : 7-alpha, 25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9H2F3

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA)

Immunogen Species: Human

Applications: ELISA, WB, IF

Tested Applications: ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IF:1:50-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction