Cusabio Recombinant Antibodies
HNRNPK Antibody | CSB-RA010611A0HU
- SKU:
- CSB-RA010611A0HU
- Availability:
- 3 to 7 Working Days
Description
HNRNPK Antibody | CSB-RA010611A0HU | Cusabio
HNRNPK Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Antibody Type: Recombinant Antibody
Target Names: HNRNPK
Aliases: Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK
Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Isotype: Rabbit IgG
Conjugate: Non-conjugated
Clonality: Monoclonal
Clone Number: 3G7
Uniport ID: P61978
Modified: Epigenetics and Nuclear Signaling
species: Human
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human HNRNPK
Tested Applications: ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.