GRIN2B (Ab-1303) Antibody | CSB-PA149419

GRIN2B (Ab-1303) Antibody | CSB-PA149419 | Cusabio

GRIN2B (Ab-1303) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: GRIN2B

Aliases: Glutamate [NMDA] receptor subunit epsilon 2 precursor; GRIN2B; hNR3; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subtype 2B

Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death By similarity.

Lasky L.A., J. Biol. Chem. 275:21477-21485 (2000) .
Mandich P., Neurosci. Lett. 239:49-53 (1997) .
Ajmar F., Genomics 22:216-218 (1994) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q13224

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized non-phosphopeptide derived from human GRIN2B around the phosphorylation site of serine 1303 (Q-H-S (p) -Y-D) .

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience