GPR143 Antibody | CSB-PA009758LA01HU

GPR143 Antibody | CSB-PA009758LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: GPR143

Aliases: G-protein coupled receptor 143 (Ocular albinism type 1 protein), GPR143, OA1

Background: Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca (2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G (q) -mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P51810

Host Species: Rabbit

Species Reactivity: Human, Rat

Immunogen: Recombinant Human G-protein coupled receptor 143 protein (314-404AA)

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB; Recommended dilution: WB:1:500-1:5000

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience