GAR1 Antibody, Biotin conjugated | CSB-PA878917LD01HU

GAR1 Antibody, Biotin conjugated | CSB-PA878917LD01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: GAR1

Aliases: H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1), GAR1, NOLA1

Background: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q9NY12

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human H/ACA ribonucleoprotein complex subunit 1 protein (1-217AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling