Cusabio Polyclonal Antibodies
FGFR1 Antibody | CSB-PA086441
- SKU:
- CSB-PA086441
- Availability:
- 3 to 7 Working Days
Description
FGFR1 Antibody | CSB-PA086441 | Cusabio
FGFR1 Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: FGFR1
Aliases: fibroblast growth factor receptor 1
Background: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: P11362
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Fusion protein of human FGFR1
Immunogen Species: Human
Applications: ELISA, IHC
Tested Applications: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:50-1:300
Purification Method: Antigen affinity purification
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: IHC:1:50-1:300
Dilution Ratio3:
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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cardiovascular
Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Cardiovascular;Signal transduction