FBP1 Antibody | CSB-PA008459ESR2HU

FBP1 Antibody | CSB-PA008459ESR2HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: FBP1

Aliases: Fructose-1, 6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase), FBP1, FBP

Background: Catalyzes the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P09467

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Fructose-1, 6-bisphosphatase 1 protein (1-338AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Metabolism;Signal transduction