EPRS Antibody, HRP conjugated | CSB-PA007747LB01HU

EPRS Antibody, HRP conjugated | CSB-PA007747LB01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: EPRS

Aliases: Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) ; Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) ], EPRS, GLNS PARS QARS QPRS

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: P07814

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Bifunctional glutamate/proline--tRNA ligase protein (1207-1399AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling