DHRS2 Antibody | CSB-PA273664

DHRS2 Antibody | CSB-PA273664 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: DHRS2

Aliases: dehydrogenase/reductase (SDR family) member 2; dehydrogenase/reductase SDR family member 2; HEP27; protein D; SDR25C1

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3, 4-Hexanedione, 2, 3-Heptanedione and 1-Phenyl-1, 2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

Gabrielli F., Eur. J. Biochem. 232:473-477 (1995) .
Pellegrini S., Biochim. Biophys. Acta 1574:215-222 (2002) .
Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q13268

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human DHRS2.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3:

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Metabolism;Signal transduction