DCC Antibody | CSB-PA081145

DCC Antibody | CSB-PA081145 | Cusabio

DCC Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: DCC

Aliases: colorectal cancer suppressor; deleted in colorectal carcinoma; netrin receptor DCC; tumor suppressor protein DCC;

Background: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

Hedrick L., Genes Dev. 8:1174-1183 (1994) .
Cho K.R., Genomics 19:525-531 (1994) .
Sjoeblom T., Science 314:268-274 (2006) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P43146

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized peptide derived from internal of human DCC.

Immunogen Species: Human

Applications: ELISA, IF

Tested Applications: ELISA, IF;IF:1:100-1:500

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IF:1:100-1:500

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Cell biology