Cusabio Polyclonal Antibodies
Capsid protein VP1 Antibody, FITC conjugated | CSB-PA362102LC01HPM
- SKU:
- CSB-PA362102LC01HPM
- Availability:
- 3 to 7 Working Days
Description
Capsid protein VP1 Antibody, FITC conjugated | CSB-PA362102LC01HPM | Cusabio
Capsid protein VP1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names:
Aliases: Capsid protein VP1 (Coat protein VP1) [Cleaved into: Capsid protein VP2 (Coat protein VP2) ]
Background: Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors, such as the glycosphingolipid globoside or the integrin heterodimer ITGAV/ITGB1. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal (s) . VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell. Intracytoplasmic transport involves microtubules and interaction between capsid proteins and host dynein. Exposure of nuclear localization signal probably allows nuclear import of capsids (By similarity) .
Isotype: IgG
Conjugate: FITC
Clonality: Polyclonal
Uniport ID: P07299
Host Species: Rabbit
Species Reactivity: Human parvovirus B19
Immunogen: Recombinant Human parvovirus B19 Capsid protein VP2 protein (228-781AA)
Immunogen Species: Human parvovirus B19
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Dilution Ratio1:
Dilution Ratio2:
Dilution Ratio3:
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others