CACNA1H Antibody | CSB-PA154566

CACNA1H Antibody | CSB-PA154566 | Cusabio

CACNA1H Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: CACNA1H

Aliases: CAC1H; CACNA1HB; calcium channel; voltage-dependent; alpha 1H subunit

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1Hgives rise to T-type calcium currents. T-type calcium channels belong to the low-voltage activated (LVA) " group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Cribbs L.L., Circ. Res. 83:103-109 (1998) .
Cribbs L.L., Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Williams M.E., J. Neurochem. 72:791-799 (1999) .
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Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O95180

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthesized peptide derived from internal of human CACNA1H.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3:

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Signal transduction