BAX Antibody | CSB-PA167247

BAX Antibody | CSB-PA167247 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: BAX

Aliases: Apoptosis regulator BAX; membrane isoform alpha; BAXA; Bcl2-associated X protein;

Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Francesca Andriani, J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324.
H Martinez-Valdez, J. Exp. Med., Mar 1996; 183: 971.
Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.
Renren Wen, Mol. Cell. Biol., Jan 2001; 21: 678 - 689.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q07812

Host Species: Rabbit

Species Reactivity: Human, Rat

Immunogen: Synthesized peptide derived from human Bax.

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF

Tested Applications: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3: IHC:1:50-1:200

Dilution Ratio4: IF:1:100-1:200

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cancer;Cell biology;Metabolism