Cusabio Polyclonal Antibodies
BAX Antibody | CSB-PA141614
- SKU:
- CSB-PA141614
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
BAX Antibody | CSB-PA141614 | Cusabio
BAX Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: BAX
Aliases: Apoptosis regulator BAX; BAX;
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Oltvai Z.N., Cell 74:609-619 (1993) .
Apte S.S., Genomics 26:592-594 (1995) .
Shi B., Biochem. Biophys. Res. Commun. 254:779-785 (1999) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q07814
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from internal of human BAX.
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF
Tested Applications: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:3000
Dilution Ratio3: IHC:1:50-1:100
Dilution Ratio4: IF:1:100-1:500
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cancer;Cell biology;Metabolism