BARD1 Antibody, FITC conjugated | CSB-PA860351LC01HU

BARD1 Antibody, FITC conjugated | CSB-PA860351LC01HU | Cusabio

BARD1 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: BARD1

Aliases: BRCA1-associated RING domain protein 1, RING-type E3 ubiquitin transferase BARD1, , BARD1

Background: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q99728

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human BRCA1-associated RING domain protein 1 protein (428-777AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Cell biology;Metabolism