B4GAT1 Antibody | CSB-PA002499EA01HU

B4GAT1 Antibody | CSB-PA002499EA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: B4GAT1

Aliases: Beta-1, 4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1, 3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 1), B4GAT1, B3GNT1 B3GNT6

Background: Beta-1, 4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1) . Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1, 4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O-mannosyl glycan (PubMed:25279699, PubMed:25279697) . Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697) . Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O43505

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Beta-1, 4-glucuronyltransferase 1 protein (161-415AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

Dilution Ratio4:

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Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Metabolism;Signal transduction