Cusabio Polyclonal Antibodies
ASPN Antibody, FITC conjugated | CSB-PA002230LC01HU
- SKU:
- CSB-PA002230LC01HU
- Availability:
- 3 to 7 Working Days
Description
ASPN Antibody, FITC conjugated | CSB-PA002230LC01HU | Cusabio
ASPN Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: ASPN
Aliases: Asporin (Periodontal ligament-associated protein 1) (PLAP-1), ASPN, PLAP1 SLRR1C
Background: Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity) . Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.
Isotype: IgG
Conjugate: FITC
Clonality: Polyclonal
Uniport ID: Q9BXN1
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Asporin protein (33-380AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction