APIP Antibody | CSB-PA839332ESR1HU

APIP Antibody | CSB-PA839332ESR1HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: APIP

Aliases: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP), APIP

Background: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2, 3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) . Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q96GX9

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Methylthioribulose-1-phosphate dehydratase protein (1-242AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology