ANTXR1 Antibody | CSB-PA276953

ANTXR1 Antibody | CSB-PA276953 | Cusabio

ANTXR1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ANTXR1

Aliases: anthrax toxin receptor 1

Background: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9H6X2

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Fusion protein of human ANTXR1

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:2000-1:5000

Dilution Ratio2: WB:1:200-1:1000

Dilution Ratio3: IHC:1:25-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Tags & Cell Markers

Research Areas: Cardiovascular;Tags & Cell Markers;Microbiology