AIM2 Antibody, HRP conjugated | CSB-PA001499LB01HU

AIM2 Antibody, HRP conjugated | CSB-PA001499LB01HU | Cusabio

AIM2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: AIM2

Aliases: Interferon-inducible protein AIM2 (Absent in melanoma 2), AIM2

Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity) . Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: O14862

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Interferon-inducible protein AIM2 protein (81-326AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling;Cancer