ACTN4 Antibody, Biotin conjugated | CSB-PA00819D0Rb

ACTN4 Antibody, Biotin conjugated | CSB-PA00819D0Rb | Cusabio

ACTN4 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ACTN4

Aliases: Alpha-actinin-4 (Non-muscle alpha-actinin 4), ACTN4

Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable) . Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161) . Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity) . May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O43707

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Alpha-actinin-4 protein (6-277AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Metabolism;Signal transduction