AANAT Antibody | CSB-PA231814

AANAT Antibody | CSB-PA231814 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: AANAT

Aliases: aralkylamine N-acetyltransferase

Background: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q16613

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Fusion protein of human AANAT

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:50-1:200

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:5000

Dilution Ratio2: IHC:1:50-1:200

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Cancer;Metabolism