WT1 Antibody | CSB-RA950156A0HU
- 3 to 7 Working Days
WT1 Antibody | CSB-RA950156A0HU | Cusabio
WT1 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant
Target Names: WT1
Aliases: Wilms tumor protein (WT33), WT1
Background: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
Isotype: Rabbit IgG
Clone Number: 5F2
Uniport ID: P19544
Modified: Epigenetics and Nuclear Signaling; Cancer; Developmental biology; Tags & Cell Markers
species: Homo sapiens (Human)
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human Wilms Tumor Protein
Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.