TRAP1 Antibody | CSB-PA03604A0Rb

TRAP1 Antibody | CSB-PA03604A0Rb | Cusabio

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Product Type: Polyclonal Antibody

Target Names: TRAP1

Aliases: Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1), TRAP1, HSP75

Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q12931

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Heat shock protein 75 kDa, mitochondrial protein (60-308AA)

Immunogen Species: Human

Applications: ELISA, WB, IF, IP

Tested Applications: ELISA, WB, IF, IP; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200, IP:1:200-1:2000

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IF:1:50-1:200

Dilution Ratio4: IP:1:200-1:2000

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Cell biology;Metabolism;Signal transduction