Cusabio Polyclonal Antibodies
SAMHD1 Antibody, Biotin conjugated | CSB-PA020691LD01HU
- 3 to 7 Working Days
SAMHD1 Antibody, Biotin conjugated | CSB-PA020691LD01HU | Cusabio
SAMHD1 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: SAMHD1
Aliases: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1), SAMHD1, MOP5
Background: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507) . Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827) .
Uniport ID: Q9Y3Z3
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (1-314AA)
Immunogen Species: Homo sapiens (Human)
Tested Applications: ELISA
Purification Method: >95%, Antigen Affinity purified & Affinity purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal Transduction