ROS1 Antibody | CSB-PA874445LA01DOA
- 3 to 7 Working Days
ROS1 Antibody | CSB-PA874445LA01DOA | Cusabio
ROS1 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: ROS1
Aliases: Protein ROS1 (EC 3.2.2.-) (DEMETER-like protein 1) (Repressor of silencing 1), ROS1, DML1
Background: Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767) . Generates 3'-phosphor-alpha, beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464) . Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752) .
Uniport ID: Q9SJQ6
Host Species: Rabbit
Species Reactivity: Arabidopsis thaliana
Immunogen: Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
Immunogen Species: Arabidopsis thaliana
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others