ROS1 Antibody | CSB-PA874445LA01DOA

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€315.80 - €488.70
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ROS1 Antibody | CSB-PA874445LA01DOA | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ROS1

Aliases: Protein ROS1 (EC 3.2.2.-) (DEMETER-like protein 1) (Repressor of silencing 1), ROS1, DML1

Background: Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767) . Generates 3'-phosphor-alpha, beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464) . Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9SJQ6

Host Species: Rabbit

Species Reactivity: Arabidopsis thaliana

Immunogen: Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)

Immunogen Species: Arabidopsis thaliana

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others

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