Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (RELT), partial | CSB-RP081794h
- 13 - 23 Working Days
Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (RELT), partial | CSB-RP081794h | Cusabio
Alternative Name(s): Receptor expressed in lymphoid tissues
Gene Names: RELT
Research Areas: Signal Transduction
Organism: Homo sapiens (Human)
AA Sequence: STTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGGETRQPGNGTRA
Tag Info: N-terminal 6xHis-tagged
Expression Region: 26-153aa
Sequence Info: Partial
MW: 17.7 kDa
Purity: Greater than 90% as determined by SDS-PAGE.
Relevance: Mediates activation of NF-kappa-B. May play a role in T-cell activation.
Reference: RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB.Sica G.L., Zhu G., Tamada K., Liu D., Ni J., Chen L.Blood 97:2702-2707(2001)
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function: Mediates activation of NF-kappa-B. May play a role in T-cell activation.
Involvement in disease:
Subcellular Location: Cell membrane, Single-pass type I membrane protein, Cytoplasm
Protein Families: RELT family
Tissue Specificity: Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas.
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: Q969Z4
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM