Recombinant Human Ciliary neurotrophic factor protein (CNTF) (Active) | CSB-AP002841HU
- 5 to 10 Working Days
Recombinant Human Ciliary neurotrophic factor protein (CNTF) (Active) | CSB-AP002841HU | Cusabio
Protein Description: Full Length
Alternative Name (s) : CNTF,
Gene Names: CNTF
Research Areas: Neuroscience
Species: Homo sapiens (Human)
Tag Info: Tag-Free
Expression Region: 1-200aa
Sequence Info: MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 150 ng/ml, corresponding to a specific activity of ＞ 6.7 × 103 IU/mg.
MW: 22.9 kDa
Purity: >97% as determined by SDS-PAGE and HPLC.
Endotoxin: Less than 1.0 EU/µg as determined by LAL method.
Relevance: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
PubMed ID: 1861138; 1915374; 1840538; 1883844; 8075647; 14702039; 15489334; 7796798; 10391209
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Function: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Involvement in disease:
Subcellular Location: Cytoplasm
Protein Families: CNTF family
Tissue Specificity: Nervous system.
Form: Lyophilized powder
Buffer: Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Uniprot ID: P26441
Uniprot Entry Name: CNTF_HUMAN
HGNC Database Link: HGNC
UniGene Database Link: UniGene
KEGG Database Link: KEGG
STRING Database Link: STRING
OMIM Database Link: OMIM