Recombinant Chlamydophila psittaci Major outer membrane porin (ompA) | CSB-EP310272CJB

Recombinant Chlamydophila psittaci Major outer membrane porin (ompA) | CSB-EP310272CJB | Cusabio

Alternative Name(s): omp1

Gene Names: ompA

Research Areas: Microbiology

Organism: Chlamydophila psittaci (Chlamydia psittaci)

AA Sequence: LPVGNPAEPSLLIDGTMWEGASGDPCDPCATWCDAISIRAGFYGDYVFDRILKVDVNKTISGMAAAPTAASGTASNTTVAADRSNFAYGKHLQDAEWCTNAAYLALNIWDRFDVFCTLGASNGYFKASSDAFNLVGLIGLAGTDFANQRPNVEISQGIVELYTDTAFSWSVGARGALWECGCATLGAEFQYAQSNPKIEMLNVTSSPAQFMIHKPRGYKGTAANFPLPVAAGTATATDTKSATVKYHEWQVGLALSYRLNMLVPYIGVNWSRATFDADTIRIAQPKLASAILNLTTWNPTLLGVATTLDTSNKYADFMQIVSMQINKMKSRKACGIAVGATLIDADKWSITGEARLIDERAAHINAQFRF

Source: E.coli

Tag Info: N-terminal 10xHis-tagged

Expression Region: 23-392aa

Sequence Info: Full Length of Mature Protein

MW: 45.4 kDa

Purity: Greater than 85% as determined by SDS-PAGE.

Relevance: In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan Permits diffusion of specific solutes through the outer membrane.

Reference: "Evidence for Chlamydia pneumoniae of non-human origin." Storey C., Lusher M., Yates P., Richmond S. J. Gen. Microbiol. 139:2621-2626(1993)

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.

Function: In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).

Involvement in disease:

Subcellular Location: Cell outer membrane, Multi-pass membrane protein

Protein Families: Chlamydial porin (CP) (TC 1.B.2) family

Tissue Specificity:

Paythway:

Form: Liquid or Lyophilized powder

Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Uniprot ID: Q00087

HGNC Database Link: N/A

UniGene Database Link: N/A

KEGG Database Link: N/A

STRING Database Link: N/A

OMIM Database Link: N/A