lexA Antibody, Biotin conjugated | CSB-PA363985HD01ENV

lexA Antibody, Biotin conjugated | CSB-PA363985HD01ENV | Cusabio

lexA Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: lexA

Aliases: LexA repressor (EC 3.4.21.88), lexA, exrA spr tsl umuA

Background: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment (PubMed:20005847) .The SOS response controls an apoptotic-like death (ALD) induced (in the absence of the mazE-mazF toxin-antitoxin module) in response to DNA damaging agents that is mediated by RecA and LexA (PubMed:22412352) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: P0A7C2

Host Species: Rabbit

Species Reactivity: Escherichia coli

Immunogen: Recombinant Escherichia coli LexA repressor protein (1-202AA)

Immunogen Species: Escherichia coli

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others