CD46 Antibody | CSB-PA004939EA01HU

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CSB-PA004939EA01HU
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3 to 7 Working Days
  • CD46 Antibody
  • Western Blot<br />
 Positive WB detected in: Hela whole cell lysate, Mouse liver tissue<br />
 All lanes: CD46 antibody at 3µg/ml<br />
 Secondary<br />
 Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
 Predicted band size: 44, 45, 43, 41, 42, 40, 37 kDa<br />
 Observed band size: 44 kDa<br />
  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA004939EA01HU at dilution of 1:100
€315.80 - €488.70
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Description

CD46 Antibody | CSB-PA004939EA01HU | Cusabio

CD46 Antibody is Available at Gentaur Genprice with the fastest delivery.

Online Order Payment is possible or send quotation to info@gentaur.com.

Product Type: Polyclonal Antibody

Target Names: CD46

Aliases: Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46), CD46, MCP MIC10

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P15529

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Membrane cofactor protein (164-325AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology

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